Systematic Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis
J. Wei, J. Moon, Y. Yasumizu, L. Zhang, K. Radassi, N. Buitrago-Pocasangre, M. E. Deerhake, N. Strauli, A. Chan, A. Herman, R. Pedotti, C. Raposo, I. Yim, J. Pappalardo, E. E. Longbrake, , D. A. Hafler
This study uses single-cell RNA sequencing to analyze immune changes after B-cell depletion in MS patients, revealing cell type-specific effects on macrophages, monocytes, and T cells.
bioRxiv · Feb 7, 2024 · PreprintImmunology