Loss of MLKL Decreases Necrotic Core but Increases Macrophage Lipid Accumulation In Atherosclerosis
A. Rasheed, S. Robichaud, M.-A. Nguyen, M. Geoffrion, M. L. Cottee, T. Dennison, A. Pietrangelo, R. Lee, M. Ouimet, K. Rayner
This study shows that reducing MLKL in atherosclerosis decreases necrotic cores but increases macrophage lipid accumulation, revealing a novel role for MLKL in lipid uptake.
bioRxiv · Aug 28, 2019 · PreprintPathology