Cardiac RyR N-terminal region biosensors for FRET-based high-throughput screening
J. Zhang, S. M. W. K. Yuen, J. A. Schwarz, L. M. Treinen, C.-C. Tung, R. T. Rebbeck, K. Ro?man, B. Svensson, C. C. Aldrich, D. D. Thomas, F. Van Petegem, R. L. Cornea
This study develops FRET-based biosensors to screen for RyR modulators, identifying novel inhibitors and activators with therapeutic potential.
bioRxiv · Feb 7, 2021 · PreprintBiophysics