ImmunologybioRxiv
Soluble signal inhibitory receptor on leukocytes-1 is released from activated neutrophils by proteinase 3 cleavage
H. J. von Richthofen, G. H. A. Westerlaken, D. Gollnast…·L. Meyaard
The paper shows that activated neutrophils release soluble SIRL-1 via proteinase 3 cleavage, and that sSIRL-1 is present in vivo in RSV and COVID-19 patients.
DOI 10.4049/jimmunol.2200169