MicrobiologybioRxiv
The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state
S. Atwal, J. Wongsantichon, S. Giengkam…·J. Salje
This paper identifies and characterizes two distinct developmental forms of Orientia tsutsugamushi, intracellular and extracellular bacteria, showing differences in morphology, protein expression, and entry mechanisms into host cells.
DOI 10.1038/s41467-022-31176-9