Heterologous vaccination regimens with self-amplifying RNA and Adenoviral COVID vaccines induce robust immune responses in mice
A. J. Spencer, P. F. McKay, S. Belij-Rammerstorfer, M. Ulaszewska, C. D. Bissett, K. Hu, K. Samnuan, A. K. Blakney, H. R. Sharpe, D. Wright, C. Gilbride, A. Truby, E. R. Allen, S. C. Gilbert, R. J. Shattock, T. Lambe
This study shows that heterologous vaccination with self-amplifying RNA and adenoviral SARS-CoV-2 vaccines in mice produces stronger antibody and cellular immune responses than single-dose regimens.
bioRxiv · Jan 28, 2021Immunology