K. Slater

Inhibition of Metastatic Uveal Melanoma Cell Proliferation by the Histone Deacetylase 6 Inhibitor, Ricolinostat, is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression

This study shows that ACY-1215 inhibits metastatic uveal melanoma cell growth in vitro and in vivo by reducing p-ERK and MITF signaling.

High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.

This paper shows high CysLT1 receptor expression in uveal melanoma correlates with poor survival and that CysLT1 antagonists inhibit tumor growth and alter cancer secretome and metabolism.

Pharmacological Restoration of Visual Function in a Zebrafish Model of von-Hippel Lindau Disease

This study shows that sunitinib restores visual function and corrects vascular abnormalities in vhl-/- zebrafish, suggesting its potential therapeutic use for VHL-related retinal issues.