K. Sneppen

The dynamics of phage predation on a microcolony

The paper experimentally quantifies phage predation on E. coli microcolonies and uses a model to show that T4 phage can penetrate deep enough to threaten colony survival despite shielding.

Emergence of networks of shared restriction-modification systems in phage-bacteria ecosystems

The paper analyzes RM system sharing in bacterial strains and models phage-bacteria dynamics to identify non-random network structures and two bacterial strategies.

The timing of natural killer cell response in coronavirus infection: a concise model perspective

The paper develops a mathematical model to analyze IFN-I signaling and its impact on coronavirus infection dynamics, predicting disease severity and chronic states based on NK cell and macrophage interactions.

On phage adsorption to bacterial chains

The paper investigates how bacterial spatial arrangements affect phage adsorption rates and shows that clustered structures significantly reduce adsorption and increase superinfection rates.

The uneasy coexistence of predators and pathogens

The paper analyzes a predator-prey model with disease in both species, finding that specialist predators are more likely to go extinct due to epidemics, while generalist predators can survive.

Regime shifts in a phage-bacterial ecosystem and strategies for its control

The paper studies regime shifts in phage-bacterial ecosystems and proposes a phage therapy strategy using partially resistant host bacteria to control bacterial populations.

Sustainability of spatially distributed bacteria-phage systems

The paper models spatially distributed bacteria-phage systems to show that spatial separation and colony growth protect bacteria from phage-driven extinction.

Theoretical Tool Bridging Cell Polarities with Development of Robust Morphologies

The paper proposes a theoretical framework linking cell polarities to morphological stability and diversity, suggesting polar adhesion strength and proliferation rates as key factors.

Hitchhiking, collapse and contingency in phage infections of migrating bacterial populations

The paper studies phage infection dynamics in migrating bacterial populations and identifies a phage transition where bacteria shift from outrunning phages to evolving resistance.

A Growing Microcolony can Survive and Support Persistent Propagation of Virulent Phages

The paper shows that larger bacterial colonies can survive virulent phages by outgrowing surface infections, with a critical size threshold identified through mathematical modeling.

Existence and construction of large stable food webs

This paper constructs large stable food webs using classical Lotka-Volterra equations by sequentially adding species and demonstrating stability through weak interactions.