Bipartite recruitment of PCH2 and COMET to the synaptonemal complex drives chromosome axis reconstruction leading to crossover restriction
C. Yang, K. Sofroni, Y. Hamamura, B. Hu, H. Tuncay Elbasi, M. Balboni, M. Heese, A. Schnittger
This study shows that PCH2 and COMET are recruited to the synaptonemal complex via ZYP1 to regulate ASY1 removal and crossover restriction during meiosis.
bioRxiv · Mar 23, 2022Cell Biology