Cellular RNA interacts with MAVS to promote antiviral signaling
N. S. Gokhale, K. Somfleth, M. G. Thompson, R. K. Sam, D. M. Marciniak, L. H. Chu, M. Park, S. Dvorkin, A. Oberst, S. M. Horner, S.-E. Ong, M. Gale, R. Savan
The paper shows that cellular RNA interacts with MAVS to scaffold signaling proteins and promote antiviral signaling by facilitating IRF3 phosphorylation.
bioRxiv · Sep 25, 2023 · PreprintImmunology