Author

K. T. Wanner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:rat· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. G. W. Gertzen· 2 shared D. Steinritz· 2 shared F. F. Paintner· 2 shared F. Worek· 2 shared H. Gohlke· 2 shared J. Kaiser· 2 shared K. V. Niessen· 2 shared T. Seeger· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

C. G. W. Gertzen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor

V. Nitsche, G. Hoefner, J. Kaiser, C. G. W. Gertzen, T. Seeger, K. V. Niessen, D. Steinritz, F. Worek, H. Gohlke, F. F. Paintner, K. T. Wanner

The paper establishes MS Binding Assays using UNC0642 as a reporter ligand to study the MB327 binding site of the nicotinic acetylcholine receptor, showing its effectiveness in both in vitro and in silico studies.

Toxicology Letters · Feb 1, 2024Peer-reviewedPharmacology & Toxicology

Identification of ligands binding to MB327-PAM-1, a binding pocket relevant for resensitization of nAChRs

J. Kaiser, C. G. W. Gertzen, T. Bernauer, V. Nitsche, G. Höfner, K. V. Niessen, T. Seeger, F. F. Paintner, K. T. Wanner, D. Steinritz, F. Worek, H. Gohlke

This paper identifies novel ligands binding to MB327-PAM-1, a binding site for resensitizing nAChRs, including cycloguanil, which shows higher affinity and functional efficacy.

bioRxiv · Dec 21, 2023Pharmacology & Toxicology