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K. W. Greeson

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Biochemistry· 1

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Approach:experimental assay· 1

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D. M. Fialho· 1 shared G. B. Schuster· 1 shared I. Martinez· 1 shared N. V. Hud· 1 shared R. Krishnamurthy· 1 shared S. Karunakaran· 1 shared

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1 shared paperBiochemistry

D. M. Fialho

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BiochemistrybioRxivSep 1, 2020

Depsipeptide nucleic acids: prebiotic formation, oligomerization, and self-assembly of a new candidate proto-nucleic acid

N. V. Hud, D. M. Fialho, S. Karunakaran…·R. Krishnamurthy

This study introduces depsipeptide nucleic acid as a prebiotic candidate for the first informational polymer, showing its spontaneous formation and self-assembly under plausible early Earth conditions.

DOI 10.1021/jacs.1c02287

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