Author

I. Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Ecology· 2 Biochemistry· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. M. Horspool· 3 shared F. H. Damron· 3 shared H. A. Cyphert· 3 shared J. R. Bevere· 3 shared M. T. Winters· 3 shared B. P. Russ· 2 shared J. Denvir· 2 shared K. S. Lee· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. M. Horspool

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Spatiotemporal dynamic models of Amblyomma americanum questing activity in the Central Great Plains

M. E. Cobos, T. Winters, I. Martinez, Y. Yao, X. Xiao, A. Ghosh, K. Sundstrom, K. Duncan, R. E. Brennan, S. E. Little, A. T. Peterson

This study models the spatiotemporal dynamics of Amblyomma americanum questing activity using longitudinal sampling, randomization tests, and presence-absence modeling to improve understanding of tick-borne disease risk.

bioRxiv · May 14, 2024 · PreprintEcology

Transposition, duplication, and divergence of the telomerase RNA underlies the Mimulus telomere evolution

S. Kumawat, I. Martinez, D. Logeswaran, H. Chen, J. Coughlan, J. Chen, Y.-w. Yuan, J. Sobel, J. Y. Choi

The paper identifies transposition, duplication, and divergence of the telomerase RNA as the mechanism driving telomere sequence evolution in Mimulus species.

bioRxiv · Dec 6, 2023 · PreprintEvolutionary Biology

Historical use of coastal wetlands by small-scale fisheries in the Northern Gulf of California

H. N. Morzaria-Luna, M. Urquidi, G. Cruz-Pinon, J. M. Dorantes Hernandez, P. A. Valdivia Jimenez, A. Sanchez Cruz, I. Martinez

The paper uses local ecological knowledge to analyze historical changes in coastal wetland fisheries in the Northern Gulf of California, finding declining species abundance and shifting baselines.

bioRxiv · Oct 31, 2022 · PreprintEcology

Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2

K. Lee, B. Russ, T. Wong, A. M. Horspool, M. T. Winters, M. Barbier, J. R. Bevere, I. Martinez, F. H. Damron, H. A. Cyphert

This study shows that diet-induced obesity and type 2 diabetes in female mice worsen SARS-CoV-2 disease outcomes compared to males and normal diet mice.

bioRxiv · Apr 26, 2022 · PreprintImmunology

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

K. S. Lee, T. Y. Wong, B. P. Russ, A. M. Horspool, O. Miller, N. Rader, J. P. Givi, M. T. Winters, Z. Y. Wong, H. A. Cyphert, J. Denvir, P. G. Stoilov, M. Barbier, N. Roan, M. S. Amin, , F. H. Damron

This study compares the pathogenesis of SARS-CoV-2 Delta and Alpha variants in K18-hACE2 mice, finding Delta causes more inflammation, tissue damage, and interferon responses.

bioRxiv · Jan 18, 2022Immunology

Prenatal cadmium exposure alters proliferation in mouse CD4+ T cells via LncRNA Snhg7

J. L. McCall, M. E. Varney, S. A. Dziadowicz, C. Hall, K. E. Blethen, G. Hu, J. B. Barnett, I. Martinez

This study shows prenatal cadmium exposure increases lncSnhg7 and GALNT7 in mouse CD4+ T cells, enhancing proliferation through miR-34a regulation.

bioRxiv · Jun 4, 2021Immunology

SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy

A. M. Horspool, C. Ye, T. Y. Wong, B. P. Russ, K. S. Lee, M. T. Winters, J. R. Bevere, T. Kieffer, I. Martinez, J. Sourimant, A. L. Greninger, R. K. Plemper, J. Denvir, H. A. Cyphert, J. B. Torrelles, , F. H. Damron

This study compares the pathogenicity and immune response of SARS-CoV-2 variants B.1.1.7 and B.1.351 with WA-1 in mice, showing reduced protection from convalescent plasma against the variants.

bioRxiv · May 5, 2021 · PreprintMicrobiology

Depsipeptide nucleic acids: prebiotic formation, oligomerization, and self-assembly of a new candidate proto-nucleic acid

N. V. Hud, D. M. Fialho, S. Karunakaran, K. W. Greeson, I. Martinez, G. B. Schuster, R. Krishnamurthy

This study introduces depsipeptide nucleic acid as a prebiotic candidate for the first informational polymer, showing its spontaneous formation and self-assembly under plausible early Earth conditions.

bioRxiv · Sep 1, 2020Biochemistry