Author

K. Zavala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Evolutionary Biology· 10

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Research Focus:chromatin & epigenetic regulation· 6 Approach:statistical model· 6 Organism:multiple species· 5 Research Focus:development & morphogenesis· 4 Approach:biophysical modeling· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

J. C. Opazo· 7 shared F. G. Hoffmann· 3 shared G. Mardones· 3 shared J. Opazo· 3 shared L. Vargas-Chacoff· 3 shared F. Morera· 2 shared M. Vandewege· 2 shared C. Colenso· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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7 shared papersEvolutionary Biology

J. C. Opazo

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10 papers

Recent·Most cited

Evolution of ion channels in cetaceans: A natural experiment in the tree of life

C. Uribe, M. Nery, K. Zavala, G. Mardones, G. Riadi, J. Opazo

This study examines ion channel evolution in cetaceans, finding fewer genes and more annotated channels, positive selection in key channels, and a higher gene turnover rate compared to non-cetacean mammals.

bioRxiv · Jun 15, 2023Evolutionary Biology

Sequence conservation and structural features that are common within TRP channels

D. Cabezas-Bratesco, C. K. Colenso, K. Zavala, D. Granata, V. Carnevale, J. C. Opazo, S. E. Brauchi

The paper identifies a conserved residue fingerprint in TRP channels that may explain differences in coupling strategies among subgroups.

bioRxiv · Sep 6, 2021Evolutionary Biology

Identification of multiple TAR DNA Binding Protein retropseudogene lineages during the evolution of primates

J. Opazo, K. Zavala, L. Vargas-Chacoff, F. Morera, G. Mardones

This study identifies multiple TAR DNA Binding Protein retropseudogene lineages in primate evolution, highlighting their potential regulatory roles despite lacking protein-coding function.

bioRxiv · May 24, 2021Evolutionary Biology

Independent duplications of the Golgi phosphoprotein 3 oncogene in birds

J. C. Opazo, M. W. Vandewege, J. Gutierrez, K. Zavala, L. Vargas-Chacoff, F. J. Morera, G. A. Mardones

The paper identifies three GOLPH3 genes in birds, finds independent duplications in non-paleognath groups, and highlights N-terminal variation and differential expression.

bioRxiv · Jan 31, 2021Evolutionary Biology

How many sirtuin genes are out there? evolution of sirtuin genes in vertebrates with a description of a new family member

J. C. Opazo, M. Vandewege, F. G. Hoffmann, K. Zavala, C. Melendez, C. Luchsinger, V. Cavieres, L. Vargas-Chacoff, F. Morera, P. Burgos, C. Tapia-Rojas, G. Mardones

The paper investigates the evolutionary history of sirtuin genes in vertebrates, identifying a new family member and showing at least eight paralogs traceable to a common ancestor.

bioRxiv · Jul 17, 2020Evolutionary Biology

Evolution of the DAN gene family in vertebrates

J. C. Opazo, F. G. Hoffmann, K. Zavala, S. V. Edwards

This study investigates the evolutionary history of the DAN gene family in vertebrates, revealing its monophyly and identifying new gene lineages and differential loss patterns across species.

bioRxiv · Jun 29, 2020Evolutionary Biology

Evolutionary analyses reveal independent origins of gene repertoires and structural motifs associated to fast inactivation in calcium-selective TRPV channels

L. Flores-Aldama, M. Vandewege, K. Zavala, C. Colenso, W. Gonzalez, S. Brauchi, J. C. Opazo

bioRxiv · Oct 17, 2019 · PreprintEvolutionary Biology

Evolution of Nodal and Nodal-related genes and the putative composition of the heterodimer that triggers the Nodal pathway in vertebrates

J. C. Opazo, S. Kuraku, K. Zavala, J. Toloza-Villalobos, F. G. Hoffmann

This study investigates the evolutionary history of Nodal and Nodal-related genes in vertebrates and infers the composition of Nodal pathway-activating heterodimers.

bioRxiv · Nov 30, 2018Evolutionary Biology

Phylogenetic evidence for independent origins of GDF1 and GDF3 genes in amphibians and mammals

J. C. Opazo, K. Zavala

This study shows that GDF1 and GDF3 genes in amphibians and mammals arose from independent duplications, not from a single ancestral gene, indicating they are not orthologs.

bioRxiv · Jun 16, 2018Evolutionary Biology

Evolution of the α2-adrenoreceptors in vertebrates: ADRA2D is absent in mammals and crocodiles

H. A. Cespedes, K. Zavala, J. Opazo

This study investigates the evolutionary history of 2-adrenoreceptor genes in vertebrates, identifying ADRA2D as a gene lost in mammals and crocodiles.

bioRxiv · Feb 7, 2017Evolutionary Biology