Author

K. Zeka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. F. Domingues· 2 shared B. J. Huntly· 2 shared C. Pina· 2 shared A. Curti· 1 shared A. V. Taylor· 1 shared C.-W. Suen· 1 shared D. Forte· 1 shared D. Ragusa· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. F. Domingues

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2 papers

Recent·Most cited

MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting

K. Zeka, A. V. Taylor, R. Samarista, D. Ragusa, C.-W. Suen, O. W. Cyran, A. F. Domingues, E. Meduri, B. J. Huntly, D. Forte, A. Curti, C. Pina

The paper shows that combining DNA demethylating agents with UPR targeting improves AML cell suppression beyond single-agent therapies.

bioRxiv · Jun 5, 2023 · PreprintCancer Biology

Loss Of Kat2a Enhances Transcriptional Noise And Depletes Acute Myeloid Leukemia Stem-Like Cells

A. F. Domingues, R. Kulkarni, G. Giotopoulos, S. Gupta, S. Tan, E. Foerner, R. Romano Adao, K. Zeka, B. J. Huntly, S. Prabakaran, C. Pina

This study shows that loss of Kat2a increases transcriptional noise and reduces leukemia stem-like cells in AML by disrupting transcriptional homogeneity.

bioRxiv · Oct 18, 2018Cancer Biology