Cancer BiologybioRxiv
Loss Of Kat2a Enhances Transcriptional Noise And Depletes Acute Myeloid Leukemia Stem-Like Cells
A. F. Domingues, R. Kulkarni, G. Giotopoulos…·C. Pina
This study shows that loss of Kat2a increases transcriptional noise and reduces leukemia stem-like cells in AML by disrupting transcriptional homogeneity.