K.-L. Ho

Initial Characterization of Canine T-cell Receptor Repertoires Using RNA-seq Data from Different Diseases and Tissues

This study characterizes the canine T-cell receptor repertoire using RNA-seq data from various diseases and tissues, revealing similarities and differences with human TCR repertoires.

Human basal-like breast cancer is represented by one of the two mammary tumor subtypes in dogs

The paper identifies a canine mammary tumor subtype that molecularly resembles human basal-like breast cancer, suggesting it as a potential translational model.

Canine tumor mutation rate is positively correlated with TP53 mutation across cancer types and breeds

The paper analyzes canine cancer mutation rates across breeds and cancer types, finding a positive correlation with TP53 mutations and a breed-specific mutation signature in Golden Retrievers.