MicrobiologybioRxivPreprint
CRISPR-Cas12a-Based Rapid and Sensitive Detection of rpoBL378R in Mycobacterium tuberculosis
Li Yang, Xiaoyu Li, Jing Tang…·Yanhui Yang
This paper develops a CRISPR-Cas12a-based detection system to identify the rpoBL378R mutation in Mycobacterium tuberculosis, showing high specificity and sensitivity for drug-resistant strains.