NeurosciencebioRxivPreprint
Regulation of excitatory presynaptic activity by Ambra1 protein determines neuronal networks in sex-dimorphic manner
Anes Ju, Bekir Altas, Hong Jun Rhee…·JeongSeop Rhee
This study shows that Ambra1 heterozygosity causes sex-specific reductions in excitatory synaptic activity, leading to E/I imbalance and autism-like behaviors in female mice.
DOI 10.1101/2022.12.19.521004