NeuroscienceNeurobiology of DiseasePeer-reviewed
Huntingtin is essential for synaptic plasticity in the adult hippocampus
Jessica C. Barron, Laura J. Dawson, Samantha J. Carew…·Matthew P. Parsons
This study shows that wild-type huntingtin (wtHTT) is essential for synaptic plasticity in the adult hippocampus, as its loss impairs long-term potentiation and post-tetanic potentiation.
5 citations