Molecular BiologyMolecular CellPeer-reviewed
The 9-1-1 complex protects ssDNA gaps in BRCA2-deficient cancer
Helen E. Grimsley, Katherine Courtemanche, Shane Cox…·Simon N. Powell
The paper identifies the 9-1-1 complex as essential for stabilizing ssDNA gaps in BRCA2-deficient cells through an ATR-independent mechanism, highlighting its role in preventing pathological expansion and DNA damage.
DOI 10.1016/j.molcel.2026.10.005