NeuroscienceeLifePeer-reviewed
Purinergic receptor P2RY14 cAMP signaling regulates EGFR-driven Schwann cell precursor self-renewal and nerve tumor initiation in neurofibromatosis.
Jennifer Patritti Cram, Jianqiang Wu, Shinji Kuninaka…·Nancy Ratner
This study identifies P2RY14 as a regulator of cAMP signaling in Schwann cell precursors, showing its role in self-renewal and neurofibroma initiation in NF1 mutant cells.
19 citations