NeurosciencebioRxivPreprint
C9orf72-ALS mutation drives mitophagy impairments in iNeurons
James Lee, Sarah M. Granger, Katie Roome…·Heather Mortiboys
This study shows that C9orf72-ALS mutation impairs mitophagy in iNeurons by reducing autophagosome production and ULK1 recruitment to mitochondria.
DOI 10.1101/2025.02.28.640849