Keemo Delos Santos

This study identifies miR-544a as a modulator of Wnt signaling in OA chondrocytes, showing it enhances Wnt activation and promotes catabolism.

This study identifies EphB4 as a critical mediator of pulmonary fibrosis through genetic and pharmacological approaches, showing reduced ECM gene expression and fibrotic pathology.

This study uses multi-omic approaches to analyze cellular and transcriptomic diversity in infrapatellar fat pad during knee osteoarthritis, identifying fibroblasts as key contributors to disease-related differences.

This study shows that patient-derived PRPS mutations in Drosophila cause autophagy and lysosome dysfunction, leading to sensitivity to nutrient deprivation and oxidative stress.