Author

Kevin Janssen

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:multiome· 1

Frequent Co-Authors

Douglas C. WallaceiD· 2 shared Adam A. Moverley· 1 shared Afshin BeheshtiiD· 1 shared Alain BorczukiD· 1 shared Alessia AngeliniD· 1 shared Amy ChadburniD· 1 shared Arnold Olali· 1 shared Brian K. AganiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Douglas C. WallaceORCID

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2 papers

Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedNov 27, 2024

Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph Nodes

Joseph W. Guarnieri, Michael J. Topper, Katherine Beigel…·Stephen B. Baylin

This study identifies non-canonical genes linked to RAAS overactivation in lethal COVID-19, causing multi-organ damage and mediastinal lymph node dysfunction.

32 citationstop 1%

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJun 25, 2023

A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies

Xiaolei Liu, Sudhish A. Devadiga, Robert F. Stanley…·Peter S. Klein

This study shows that SRSF2 mutations disrupt mitochondrial mRNA splicing, impair complex I function, and increase mitophagy through a PINK1 splicing mechanism, identifying mitophagy as a therapeutic target in MDS and AML.

DOI 10.1101/2023.06.25.546449

humanmultiome

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