MicrobiologyGenome biologyPeer-reviewed
Un1Cas12f1 and Cas9 gene drive in HSV1: Viruses that 'infect' viruses
Zhuangjie Lin, Qiaorui Yao, Keyuan Lai…·Hongsheng Dai
This study develops Cas9 and Un1Cas12f1 gene drives in HSV1 to assess gene drive efficacy and resistance, finding Un1Cas12f1 has higher conversion and lower resistance.