BiophysicsCell ReportsPeer-reviewed
RNA virus polymerase-helicase coupling enables rapid elongation throughduplex RNA
Pim P. B. America, Subhas Chandra Bera, Arnab Das…·David Dulin
This study shows that the coronavirus helicase enhances RNA synthesis through duplex RNA by tenfold by forming a directional complex with the polymerase, revealing an active coupling mechanism that modulates replication dynamics.
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