BiophysicsbioRxivPreprint
Kinetic asymmetry drives kinesin-1's unidirectional and processive movement
Hiroshi Isojima, Kohei Matsuzaki, Michio Tomishige
This study investigates how kinesin-1 moves unidirectionally by comparing biased-diffusion and biased-binding mechanisms, finding that kinetic asymmetry in binding and detachment drives its processive motion.
DOI 10.1101/2025.06.11.659012