Cancer BiologybioRxivPreprint
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Identification of Bone Morphogenetic Protein 7 as a Master Regulator of Gastric Cancer-Associated Cachexia
Mayu Yasuda-Koiwa, Takahiro Shoda, Akiho Nishimura…·Takatsugu Ishimoto
In a gastric cancer peritoneal dissemination mouse model, BMP7 knockdown in MKN45 cells attenuated cachexia, and BMP7 acted upstream of GDF11 and GDF15 expression.