Author

Kris Engelstad

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Michio HiranoiD· 2 shared Anna L MarslandiD· 1 shared Anna S. Monzel· 1 shared Brett A KaufmaniD· 1 shared Caroline TrumpffiD· 1 shared Catherine Kelly· 1 shared Catherine LapriseiD· 1 shared Christine Des RosiersiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Michio HiranoORCID

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Author profile →

2 papers

Recent·Most cited

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity

Owen S. Skinner, María Miranda, Fangcong Dong, Tessa Struhl, Melissa Anne Walker, Grigorij Schleifer, Matthew T. Henke, Jon Clardy, Michio Hirano, Darryl C. De Vivo, Eric A. Schon, Kris Engelstad, Stephanie Siegmund, Catherine Laprise, Christine Des Rosiers, , Rohit Sharma

This paper identifies 4,5-dihydroxyhexanoic acid as a biomarker for mitochondrial disease severity and links it to GABA metabolism.

bioRxiv · Feb 12, 2026 · PreprintBiochemistry

The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stress

Qiuhan Huang, Anna S. Monzel, Shannon Rausser, Rachel Haahr, Claire E. Indik, Micah J Savin, Natalia Bobba-Alves, Cynthia C. Liu, Jack Devine, Elizabeth Thompson, Catherine Kelly, Mangesh Kurade, Jeremy Michelson, Shufang Li, Kris Engelstad, , Caroline Trumpff

This paper shows that GDF15 levels rise with psychosocial stress, depression, anxiety, and biological aging, and that saliva GDF15 has a distinct diurnal pattern and responds rapidly to acute stress.

bioRxiv · Apr 19, 2024 · PreprintPhysiology