Cell BiologyInvestigative Ophthalmology & Visual SciencePeer-reviewed
Loss of Cathepsin K impairs collagen biogenesis and enhances actin polymerization in trabecular meshwork
Avinash Soundararajan, Krishna Jayasankar, Emma H. Doud…·Padmanabhan Paranji Pattabiraman
This study shows that loss of Cathepsin K disrupts collagen biogenesis, ECM homeostasis, and actin polymerization in trabecular meshwork cells, potentially affecting aqueous humor outflow and IOP regulation.
1 citation