BioinformaticsNucleic Acids ResearchPeer-reviewed
Direct RNA sequencing (RNA004) allows for improved transcriptome assessment and near real-time tracking of methylation for medical applications
Charlotte Hewel, Anna Wierczeiko, Johannes Miedema…·Susanne Gerber
This study evaluates improvements in direct RNA sequencing (DRS) using RNA004 chemistry and modified-base-calling models, showing enhanced throughput, accuracy, and detection of RNA modifications in clinical applications.
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