Author

Kuan-Hung Lin

University of Massachusetts Chan Medical School

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Molecular Biology· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Alicia Newton· 1 shared Ayşegül ÖzeniD· 1 shared Celia A. SchifferiD· 1 shared Christos J. PetropoulosiD· 1 shared Cihan AydıniD· 1 shared Davide TavellaiD· 1 shared Keith P. RomanoiD· 1 shared Wei HuangiD· 1 shared

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2018-2018 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Alicia Newton

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintDec 16, 2018

Resistance from Afar: Distal Mutation V36M Allosterically Modulates the Active Site to Accentuate Drug Resistance in HCV NS3/4A Protease

Ayşegül Özen, Kuan-Hung Lin, Keith P. Romano…·Celia A. Schiffer

This study investigates how the distal mutation V36M confers drug resistance in HCV NS3/4A protease through allosteric modulation of the active site, in the context of R155K.

1 citation

experimental assay

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