Auranofin shows bactericidal activity in Pseudomonas aeruginosa by targeting thiol homeostasis
Alexandre Lüscher, Yves Mattenberger, Léna Falconnet…·Thilo Köhler
This study identifies auranofin as a bactericidal agent against Pseudomonas aeruginosa by targeting thiol homeostasis, highlighting the value of overcoming efflux barriers to discover new antibiotics.