Author

L. C. Bartelt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Barrera· 1 shared C. V. Nicchitta· 1 shared H. X. Ang· 1 shared I. C. McDowell· 1 shared J. Lin· 1 shared J. Z. Sheng· 1 shared K. C. Wood· 1 shared N. Sutiman· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Barrera

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1 paper

Recent·Most cited

Cooperative regulation of coupled oncoprotein translation and stability in triple-negative breast cancer by EGFR and CDK12

H. X. Ang, N. Sutiman, X. L. Deng, L. C. Bartelt, Q. Chen, A. Barrera, J. Lin, J. Z. Sheng, I. C. McDowell, T. E. Reddy, C. V. Nicchitta, K. C. Wood

The paper identifies CDK12 inhibition as a strategy to enhance EGFR blockade efficacy in TNBC by targeting translation and stability of oncoproteins like MYC through 4E-BP1 and CCR4-NOT complex.

bioRxiv · Mar 3, 2021 · PreprintCancer Biology