Author

L. Cersosimo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Organism:mouse· 1

Frequent Co-Authors

B. Dupuy· 2 shared J. Peltier· 2 shared L. Bry· 2 shared A. Monestier· 1 shared A. Pavao· 1 shared J. N. Worley· 1 shared M. Graham· 1 shared M. Oberkampf· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

B. Dupuy

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2 papers

Recent·Most cited

The TcdE holin drives toxin secretion and virulence in Clostridioides difficile.

N. V. DiBenedetto, M. Oberkampf, L. Cersosimo, V. Yeliseyev, L. Bry, J. Peltier, B. Dupuy

This study shows that TcdE holin is essential for toxin secretion and virulence in C. difficile, as tcdE mutants exhibit reduced toxin release and less virulence in mice.

bioRxiv · Sep 16, 2023 · PreprintMicrobiology

Central in vivo mechanisms by which C. difficile's proline reductase drives efficient metabolism, growth, and toxin production

L. Cersosimo, M. Graham, A. Monestier, A. Pavao, J. N. Worley, J. PELTIER, B. Dupuy, L. Bry

This study shows that proline reductase in C. difficile is essential for metabolism, growth, and toxin production in vivo, as its absence delays colonization and disease progression in mice.

bioRxiv · May 19, 2023 · PreprintMicrobiology