Lung injury induces alveolar type 2 cell hypertrophy and polyploidy with implications for repair and regeneration
A. Weng, M. Maciel-Herrerias, S. J. Watanabe, A. S. Flozak, L. Welch, R. P. Aillon, R. Grant, S. Han, L. Dada, M. HInchcliff, A. Misharin, G. S. Budinger, C. J. Gottardi
This study shows lung injury induces alveolar type 2 cell hypertrophy and polyploidy, which can be reduced by inhibiting the integrated stress response.
American Journal of Respiratory Cell and Molecular Biology · May 1, 2022Peer-reviewedCell Biology