Cell BiologybioRxiv
SETDB1 modulates the TGFbeta response in Duchenne muscular dystrophy myotubes
A. GRANADOS, M. ZAMPERONI, R. RAPONE…·S. AIT-SI-ALI
This study shows that SETDB1 enhances TGFβ-driven fibrosis in DMD myotubes by modulating TGFβ-target gene expression and secretome effects on myoblast differentiation.
DOI 10.1126/sciadv.adj8042