How Mycobacterium tuberculosis builds a home: Single-cell analysis reveals M. tuberculosis ESX-1-mediated accumulation of anti-inflammatory macrophages in infected mouse lungs.
W. Zheng, M. Borja, L. Dorman, J. Liu, A. Zhou, A. Seng, R. Arjyal, S. Sunshine, A. Nalyvayko, A. O. Pisco, O. Rosenberg, N. Neff, B. S. Zha
This study uses single-cell RNA sequencing to show that M. tuberculosis ESX-1 promotes the recruitment and differentiation of anti-inflammatory macrophages in infected mouse lungs.
bioRxiv · Apr 20, 2024Microbiology