Author

L. Dowsett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Pilotti· 2 shared J. George· 2 shared J. Greenwood· 2 shared S. E. Moss· 2 shared A. Ager· 1 shared A. Dritsoula· 1 shared A. H. Watson· 1 shared A. Hoeh· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

C. Pilotti

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency

M. N. O'Connor, D. M. Kallenberg, R. Jackstadt, A. H. Watson, M. Alatsatianos, J. Ohme, C. Camilli, C. Pilotti, A. Dritsoula, C. E. Bowers, L. Dowsett, J. George, X. Wang, A. Ager, O. J. Sansom, , J. Greenwood

This study shows that LRG1 promotes tumor vascular dysfunction and suppresses immunotherapy effectiveness, with its inhibition enhancing therapeutic outcomes in mouse cancer models.

bioRxiv · Oct 12, 2020Cancer Biology

A Humanized Antibody against LRG1 that Inhibits Angiogenesis and Reduces Retinal Vascular Leakage

D. Kallenberg, V. Tripathi, F. Javaid, C. Pilotti, J. George, S. Davis, J. W. Blackburn, M. O'Connor, L. Dowsett, C. Bowers, S. E. Liyanage, M. Gourlaouen, A. Hoeh, F. Mota, D. Selwood, , S. E. Moss

bioRxiv · Jul 25, 2020 · PreprintPathology