Author

L. Fesus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Pap· 1 shared A. Shaw· 1 shared A. Vamos· 1 shared B. B. Toth· 1 shared B. Becsi· 1 shared E. Kristof· 1 shared F. Gyory· 1 shared I. P. Uray· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Pap

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Transglutaminase 2 associated with PI3K and PTEN in a putative membrane-bound signalosome platform blunts cell death

K. Jambrovics, P. Boto, Z. Kolostyak, S. Zsolt, A. Pap, I. Szatmari, Z. Czimmerer, I. P. Uray, L. Fesus, Z. Balajthy

This study shows that TG2 promotes cell survival in APL cells by forming a signalosome platform that hyperactivates PI3K and inhibits PTEN, reducing apoptosis.

bioRxiv · Feb 16, 2022 · PreprintCancer Biology

Biochemical characterisation of human transglutaminase 4

Z. Csoban-Szabo, B. Becsi, S. El Alaoui, L. Fesus, I. R. Korponay-Szabo, R. Kiraly

This study characterizes the biochemical properties of human transglutaminase 4, revealing its low transamidase activity, pH and reducing environment preference, and potential role as an anticancer target.

bioRxiv · Sep 1, 2021Biochemistry

FTO intronic SNP strongly influences human neck adipocyte browning determined by tissue and PPARγ specific regulation: a transcriptome analysis

B. B. Toth, R. Arianti, A. Shaw, A. Vamos, Z. Vereb, S. Poliska, F. Gyory, Z. Bacso, L. Fesus, E. Kristof

This study shows that the FTO SNP rs1421085 affects human neck adipocyte browning by regulating PPARγ-dependent gene expression and thermogenic pathways.

bioRxiv · Feb 21, 2020Cell Biology