Cancer BiologybioRxivPreprint
Transglutaminase 2 associated with PI3K and PTEN in a putative membrane-bound signalosome platform blunts cell death
K. Jambrovics, P. Boto, Z. Kolostyak…·Z. Balajthy
This study shows that TG2 promotes cell survival in APL cells by forming a signalosome platform that hyperactivates PI3K and inhibits PTEN, reducing apoptosis.
DOI 10.1101/2022.02.16.480667