Author

L. Guyon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1

Frequent Co-Authors

A. Puisieux· 2 shared F. Reyal· 2 shared L. Blanchoin· 2 shared M. Thery· 2 shared Y. Margaron· 2 shared A. Pinheiro· 1 shared A.-P. Morel· 1 shared B. RAGAZZON· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

A. Puisieux

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Plakins are involved in the maintenance of epithelial polarity

J. Geay, Y. Margaron, D. Gentien, F. Reyal, A. Puisieux, L. Blanchoin, L. Guyon, M. Thery

The paper identifies plakins as regulators of epithelial polarity by showing their downregulation in polarity loss and EMT progression, and demonstrates their causal role through experimental knockdown.

bioRxiv · Oct 16, 2023 · PreprintCell Biology

Aberrant activation of Wnt/β-Catenin signaling pathway drives the expression of poorprognosis-associated microRNAs in adrenocortical cancer with a major impacton miR-139-5p and its host gene PDE2A

J. CRISTANTE, S. REDA EL SAYED, J. DENIS, B. RAGAZZON, C. HANTEL, O. CHABRE, L. GUYON, N. CHERRADI

This study shows that Wnt/β-Catenin signaling activation in adrenocortical cancer upregulates poor-prognosis miRNAs, particularly miR-139-5p, which is linked to PDE2A repression and NDRG4 activation.

bioRxiv · Feb 10, 2023 · PreprintCancer Biology

COL7A1 expression improves prognosis prediction for patients with clear cell renal cell carcinoma atop of stage

D. Koca, I. Seraudie, R. Jardiller, C. Cochet, O. Filhol, L. Guyon

This study investigates COL7A1 expression as a prognostic marker in clear cell renal cell carcinoma, finding it stratifies patients into survival groups and impacts cell migration and proliferation.

bioRxiv · Jan 16, 2023Cancer Biology

Biophysical properties of intermediate states of EMT outperform both epithelial and mesenchymal states.

Y. Margaron, T. Nagai, L. Guyon, L. Kurzawa, A.-P. Morel, A. Pinheiro, L. Blanchoin, F. Reyal, A. Puisieux, M. Thery

The paper investigates the biophysical properties of intermediate EMT states and finds they exhibit distinct structural and mechanical features compared to epithelial and mesenchymal states, with implications for tumor-cell dissemination.

bioRxiv · Oct 8, 2019 · PreprintCell Biology