Author

O. Filhol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

C. Cochet· 2 shared C. Roelants· 2 shared A. Bancet· 1 shared A. Mularoni· 1 shared A. Seffouh· 1 shared C. Battail· 1 shared C. Pillet· 1 shared D. Koca· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

C. Cochet

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Author profile →

3 papers

Recent·Most cited

COL7A1 expression improves prognosis prediction for patients with clear cell renal cell carcinoma atop of stage

D. Koca, I. Seraudie, R. Jardiller, C. Cochet, O. Filhol, L. Guyon

This study investigates COL7A1 expression as a prognostic marker in clear cell renal cell carcinoma, finding it stratifies patients into survival groups and impacts cell migration and proliferation.

bioRxiv · Jan 16, 2023Cancer Biology

AB668, a novel highly selective protein kinase CK2 inhibitor with a distinct anti-tumor mechanism as compared to CX-4945 and SGC-CK2-1

A. Bancet, R. Frem, F. Jeanneret, A. Mularoni, P. Bazelle, C. Roelants, J.-G. Delcros, J.-F. Guichou, C. Pillet, I. Coste, T. Renno, C. Battail, C. Cochet, T. Lomberget, O. Filhol, I. Krimm

The paper introduces AB668, a selective CK2 inhibitor with a distinct anti-tumor mechanism compared to CX-4945 and SGC-CK2-1, showing apoptotic effects and pathway stimulation in cancer cells.

bioRxiv · Dec 16, 2022 · PreprintBiochemistry

Extracellular endosulfatase Sulf-2 harbours a chondroitin/dermatan sulfate chain that modulates its enzyme activity

R. El Masri, A. Seffouh, C. Roelants, I. Seffouh, E. Gout, J. Perard, F. Dalonneau, K. Nishitsuji, F. Noborn, M. Nikpour, G. Larson, Y. Cretinon, K. Uchimura, R. Daniel, H. Lortat-Jacob, , R. R. Vives

This study identifies a chondroitin/dermatan sulfate chain in Sulf-2 that modulates its enzyme activity, revealing a new paradigm for Sulfs' function.

bioRxiv · Jan 4, 2021 · PreprintBiochemistry