Cell BiologybioRxiv
O-GlcNAcylation is essential for rapid Pomc expression and cell proliferation in corticotropic tumor cells
L. J. Massman, M. Pereckas, N. T. Zwagerman, S. Olivier-Van Stichelen
This study shows O-GlcNAcylation is essential for Pomc expression and cell proliferation in corticotropic tumors, contributing to ACTH hypersecretion and Cushing's disease.
DOI 10.1210/endocr/bqab178