Hypoxia is a dominant remodeler of the CD8+ T cell surface proteome relative to activation and regulatory T cell-mediated suppression
J. R. Byrnes, A. M. Weeks, J. Carnevale, E. Shifrut, L. Kirkemo, A. Ashworth, A. Marson, J. A. Wells
This study compares how hypoxia and regulatory T cells affect the CD8+ T cell surface proteome, finding hypoxia has a more significant impact than Treg-mediated suppression.
bioRxiv · Jun 7, 2021Immunology