PhysiologyJournal of the American Heart AssociationPeer-reviewed
Extracellular RNA induce neutrophil recruitment via endothelial TLR3 during venous thrombosis after vascular injury
Maria Y. Najem, Ryan N. Rys, Sandrine Laurance…·Catherine A. Lemarié
This study shows that extracellular RNA (eRNA) promotes venous thrombosis by activating TLR3 on endothelial cells, leading to neutrophil recruitment and CXCL5 secretion.
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