Author

L. Lyons

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. M. Rafiq· 2 shared P. De Camilli· 2 shared S. Ferguson· 2 shared S. Gowrishankar· 2 shared A. Roczniak-Ferguson· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

N. M. Rafiq

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2 papers

Recent·Most cited

JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton

N. M. Rafiq, L. Lyons, S. Gowrishankar, P. De Camilli, S. Ferguson

This study shows that JIP3 depletion disrupts axonal cytoskeleton organization and causes lysosome accumulations in human neurons, linking lysosome transport to cytoskeletal regulation.

bioRxiv · Jun 24, 2020Cell Biology

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons

S. Gowrishankar, L. Lyons, N. M. Rafiq, A. Roczniak-Ferguson, P. De Camilli, S. Ferguson

This study investigates the roles of JIP3 and JIP4 in axonal lysosome transport using human iPSC-derived neurons, showing their involvement in preventing lysosome accumulation and amyloid-beta production.

bioRxiv · Jun 13, 2020Cell Biology