Cell BiologybioRxiv
Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
S. Gowrishankar, L. Lyons, N. M. Rafiq…·S. Ferguson
This study investigates the roles of JIP3 and JIP4 in axonal lysosome transport using human iPSC-derived neurons, showing their involvement in preventing lysosome accumulation and amyloid-beta production.
DOI 10.1091/mbc.e20-06-0382