BiochemistryNature CommunicationsPeer-reviewed
SCOPE: Flexible targeting and stringent CARF activation enables type III CRISPR-Cas diagnostics
J. A. Steens, Y. Zhu, D. W. Taylor…·R. H. J. Staals
This study identifies key regions in type III CRISPR-Cas systems for RNA targeting and cOA production, leading to the development of the SCOPE diagnostic tool for SARS-CoV-2 detection.
DOI 10.1038/s41467-021-25337-5